HOW TO RAISE GLUTATHIONE WITH COFACTORS
The Whey in Dairy Milk Kefir contains compounds that make Glutathione - this is your master antioxidant made in your body if you have enough ingredients and is crucial to good health. Your body is a vast chemical factory. Drink 1 cup of milk kefir every day.
Vitamins - in one trial, blood GSH levels rose nearly 50% in healthy people taking 500 mg of vitamin C per day for only two weeks. Vitamin C raises Glutathione by helping the body manufacture it.
Vitamin E acts in a similar way as vitamin C - it recycles Glutathione and depends on it for proper function and recycling as well.
Vitamins B6, B12, B1 and B2 are also required in the synthesis of Glutathione. B1 and B2 maintain Glutathione and its related enzymes in their active forms. B2 helps combine amino acids into proteins, and Glutathione is one of them. B6 is crucial for the metabolism and proper function of many amino acids, for example, for converting homocysteine into cysteine. B12 acts as a coenzyme in the production and regulation of red blood cells.
Folate or folic acid (known as B9) - its role as Glutathione booster lies in folate’s ability to divert cysteine preferentially towards Glutathione production rather than homocysteine production, thus helping supply the cells with more cysteine for building intracellular Glutathione. Maximum recommended dosage of folate is 400 mcg/day. Best dietary sources are spinach, turnip greens, lettuce, dried beans and peas, sunflower seeds, peanuts, avocado, asparagus, fortified pastas and cereals. When cooking veggies they should be steamed instead of boiled – less folate leaches into the water this way.
Selenium - the trace element that functions as an antioxidant. It also participates in protein synthesis and other metabolic processes and acts together with other antioxidants, especially vitamin E. Selenium elevates the levels of glutathione peroxidase; the cysteine molecule appearing in the process of digestion of plants grown in selenium-rich soil contributes to GSH production. Recommended Daily Intake (RDI) for adults is 55 mcg. Best dietary sources are Brazil nuts, sunflower seeds, oatmeal, tuna, turkey, chicken breast, beef, eggs and brown rice.
Magnesium - magnesium is necessary for proper functioning of enzyme gamma glutamyl transpeptidase which is important in the synthesis of Glutathione. RDI is 400 mg, but optimum daily intake is considered at 490- 700 mg. Best dietary sources are halibut, spinach, squash, pumpkin seeds, sunflower seeds, toasted sesame seeds, beans, walnuts, almonds, peanuts and Brazil nuts.
Zinc - zinc deficiency leads to low concentrations of reduced (non-oxidized) Glutathione, especially in red blood cells. This is detrimental to Glutathione metabolism. However, high levels of zinc may reduce Glutathione because zinc has a certain toxicity. RDI for adults is 8-11 mg. Best dietary sources are oysters, beef shanks, chicken legs, pork shoulder and tenderloin, and Alaskan King crab. Zinc from beans, legumes and grains has very low bioavailability compared to meat sources.
Vanadium - this element depends on Glutathione to stay in non-oxidized state and to increase vanadium’s bioavailability. It may recycle Glutathione under certain conditions. Vanadium is not considered a crucial cofactor and at high levels it may even deplete glutathione due to its toxicity. Vanadium’s role in health has not been studied very well, so there is no RDA established. Average diet provides 6-18 mcg a day. Safe upper limit is 1.8 mg (1,800 mcg). Dietary sources are: mushrooms, shellfish, dill, parsley and black pepper.
Adequate amounts of vitamins C, E, B1, B2, B6, B12, folate, selenium, magnesium and zinc, either from diet or with additional supplementation, are necessary for raising Glutathione levels.